Differential serological and neutralizing antibody dynamics after an infection by a single SARS-CoV-2 strain

We report here the case of two coworkers infected by same SARS-CoV-2 strain, presenting different immunological outcomes. One patient presented a strong IgG anti-receptor-binding domain immune response correlated with low and rapidly decreasing titer neutralizing antibodies. The other had similar but high antibody titers. Thus, host individual factors may be main drivers varying age clinical severity.